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Overview of the major steps in the pathogenesis of coronary artery disease at the local and systemic level. Flashes indicate events that were also observed after radiation exposure, and which are mainly related to inflammation. ECs, endothelial cells; LDL, low-density lipoprotein; IL-6, interleukin-6; CRP, C-reactive protein. The figure has been adapted from a previous study (3).
