Table I.
Expression profiles of cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) at 6 h after the lipopolysaccharide (LPS) (10 mg/kg) injection in wild-type (WT), CBS+/−, CSE−/− and Δ3MST mice.
| WT (%) |
CBS+/− (%) |
CSE−/− (%) |
Δ3MST (%) |
|
|---|---|---|---|---|
| CBS expression | ||||
| Spleen | 227±29a | 168±15a | 111±6 | 107±15 |
| Lung | 134±12a | 115±6 | 109±17 | 120±10 |
| Liver | 112±12 | 19±6 | 149±11a | 107±13 |
| Kidney | 112±14 | 19±5 | 161±15a | 123±9a |
| CSE expression | ||||
| Spleen | 116±14 | 125±15a | 0 | 91±9 |
| Lung | 134±19a | 92±16 | 0 | 120±6a |
| Liver | 92±5 | 101±6 | 0 | 103±22 |
| Kidney | 119±1 | 106±1.6 | 0 | 103±12 |
| 3MST expression | ||||
| Spleen | 116±8 | 125±10a | 125±11a | 1±1 |
| Lung | 177±25a | 159±20a | 241±14a | 9±1 |
| Liver | 139±9a | 129±12a | 111±11 | 107±13 |
| Kidney | 110±13 | 114±8 | 9±1 | 115±13 |
a
P<0.05 shows significant change compared to baseline control in wild-type mice (which is considered as 100%). Data are shown as the means ± standard error of the mean (SEM) of n=5 determinations; n=5.