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. 2016 Nov 21;11(11):e0167013. doi: 10.1371/journal.pone.0167013

Table 2. Total selenium, total sulfur, trimethylselenonium (TMSe), and trimethylsulfonium (TMS) in the study groups.

TMSe producers (n = 13) TMSe non-producers (n = 12) P value
Mean ± SD (range) Geo. mean (95% CI) Median Mean ± SD range Geo. mean (95% CI) Median
Total S (mg L-1) 781 ± 98 (604–956) 775 (718–837) 776 853 ± 129 (599–1004) 844 (762–936) 876 0.110
Total Se (μg L-1) 30.4 ± 12.3 (20.5–65.2) 28.7 (23.5–35.1) 25.9 23.9 ± 7.3 (15.3–40.3) 22.9 (19.0–27.6) 23.6 0.113
TMS (nM) 296 ± 202 (76.0–691) 224 (154–364) 222 31.5 ± 24.7 (4.2–69.3) 22.1 (12.1–40.4) 22.3 <0.001
TMSe (nM)* 55.4 ± 19.5 (24.3–93.6) 52.1 (41.7–65.2) 52.2 <LOQ <LOQ <LOQ -

*TMSe was detected in “TMSe non-producers” (LOD = 0.8 nM) but always fell below the limit of quantitation (LOQ = 2.6 nM). The P values are two-tailed values calculated using the nonparametric Mann-Whitney U test. The urinary level in each volunteer was calculated as the mean for the donated 5 morning urine samples.