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. 2016 Nov 2;38(6):1661–1672. doi: 10.3892/ijmm.2016.2794

Figure 2.

Figure 2

Effects of osteoprotegerin (OPG) knockout on diabetes-related osteoporosis (DO). (A) Analysis of bone volume fraction (BV/TV) in mice in the normal, DO, DO + OPG-KO, DO + 10 mg/kg bergapten (BP) and DO + 20 mg/kg BP groups. (B) Analysis of trabecular thickness (Tb.Th) in mice in the normal, DO, DO + OPG-KO, DO + 10 mg/kg BP and DO + 20 mg/kg BP groups. (C) Analysis of trabecular number (Tb.N) in mice in the normal, DO, DO + OPG-KO, DO + 10 mg/kg BP and DO + 20 mg/kg BP groups. ##p<0.01 and ###p<0.001 vs. normal group; *p<0.05; +p<0.05, ++p<0.01 and +++p<0.001. (D) X-ray scanning for determining bone mineral density. The arrows in the images indicate the bone mineral density.