Table 2. Disease-free survival and overall survival results: univariate and multivariate analysis.

	Disease-free survival			Overall survival
	Log rank	Coxa		Log rank	Coxa
	P-value	P-value	HR (95% CI)	P-value	P-value	HR (95% CI)
Age (years)
⩽40	0.073			<0.0001		1
41–75					0.083	1.62 (0.94–2.81)
>75					<0.0001	5.46 (2.50–11.9)
pT (mm)
0–10	<0.0001		1	<0.0001		1
>20		<0.0001	1.96 (1.44–2.66)		<0.0001	2.05 (1.42–2.95)
LVI
Yes vs no	<0.0001	0.001	1.68 (1.22–2.32)	<0.0001	0.003	1.76 (1.21–2.55)
pN
pN0	<0.0001		1	<0.0001		1
i+, mic		0.019	1.72 (1.1–2.71)		0.121	1.52 (0.89–2.59)
Macro		<0.0001	1.97 (1.38–2.81)		0.009	1.78 (1.15–2.74)
Grade
3 vs 1 or 2	0.047	0.169		0.018	0.017	1.67 (1.10–2.55)
Chemotherapy
No vs yes	0.622			0.744
Pathological subtype	0.433			0.565

Abbreviations: 95% CI=95% confidence interval; HR=hazard ratio; LVI=lymphovascular invasion; N=number of patients; pN=pathological lymph onde involvement; pT=pathological tumour size.

^aWald test.