Table 2.

Statistical analysis of the relationship between ¹⁸F-fluorodeoxyglucose (FDG) uptake metrics and esophagitis grade at the time of the FDG-positron emission tomography (PET) scan, and maximum treatment esophagitis grade (n = 79). Univariate logistic regression p-values reported have been corrected with the Benjamini-Hochberg false discovery rate procedure.

FDG uptake metric	≥Grade 2 during PET scan		≥Grade 2 Treatment Maximum
	P Value	AUC*	P Value	AUC*
SUVmean	2.04E-02	0.67	2.35E-01	0.61
SUVmax	5.23E-03	0.73	1.88E-03	0.75
nSUVmean†	8.16E-05	0.84	4.09E-05	0.87
nSUVmax	1.55E-04	0.82	1.26E-06	0.91
nSUVaxMax1‡	8.16E-05	0.85	1.17E-06	0.91
nSUVaxMax3	5.32E-05	0.85	9.53E-06	0.87
nSUVaxMax5	5.75E-05	0.84	1.52E-05	0.86
nSUVaxMax7	8.16E-05	0.81	3.65E-05	0.84
nSUVlen20**	5.32E-05	0.80	7.37E-06	0.89
nSUVlen30	5.32E-05	0.84	1.17E-06	0.91
nSUVlen40	8.16E-05	0.85	6.52E-08	0.92
nSUVlen50	7.15E-04	0.81	1.26E-06	0.87
nSUVlen60	1.32E-02	0.74	4.23E-05	0.80
nSUVperc65††	8.31E-05	0.83	1.12E-05	0.89
nSUVperc75	8.31E-05	0.83	2.48E-06	0.90
nSUVperc85	8.16E-05	0.84	2.48E-06	0.90
nSUVperc95	4.69E-04	0.83	1.26E-06	0.91

^*Area under the curve.

^†Voxel mean normalized standard uptake value.

^‡Axial-averaged maximum nSUV for 1, 3, 5, and 7 slices (e.g., nSUV_axMax1 for the 1-slice average).

^**Axial length of esophageal tissue with at least a given percentage of axial-averaged nSUV response (e.g., nSUV_len20 for a length of esophagus with nSUV ≥ 20% axial-averaged response over the baseline SUV value).

^††Voxel percentile nSUV values from the sixty-fifth to the ninety-fifth percentiles (e.g., nSUV_perc65 for the sixty-fifth percentile).