Table 2.

Comparisons of quantitative DWI and PWI parameters of HCC patients between the effective and ineffective groups before and after TACE

Parameter	Effective group (n=67)	Ineffective group (n=51)	t	P-value
MTD (cm)
Before TACE	5.81±2.43	6.93±2.94	2.262	0.026
After TACE	4.53±1.87*	6.07±3.27	3.233	0.002
ADC (×10−3 mm2/s)
Before TACE	1.01±0.29	0.71±0.05	7.228	<0.001
After TACE	1.32±0.15*	1.23±0.21*	2.717	0.008
Dslow (×10−3 mm2/s)
Before TACE	0.75±0.16	0.56±0.13	6.888	<0.001
After TACE	0.97±0.17*	0.88±0.27*	2.217	0.029
Dfast (×10−3 mm2/s)
Before TACE	32.97±9.26	44.58±9.94	6.524	<0.001
After TACE	21.70±6.92*	27.84±6.69*	3.562	0.001
f (%)
Before TACE	15.07±4.78	15.56±5.13	0.533	0.595
After TACE	14.72±3.87	14.91±4.26	0.252	0.801
Ktrans (/min)
Before TACE	1.74±0.08	1.66±0.06	5.655	<0.001
After TACE	1.59±0.10*	1.63±0.15	1.737	0.085
Kep (/min)
Before TACE	1.99±0.14	2.19±0.19	6.586	<0.001
After TACE	1.35±0.12*	1.50±0.42*	2.798	0.006
Ve
Before TACE	0.45±0.06	0.44±0.05	0.959	0.340
After TACE	0.43±0.07	0.42±0.08	0.707	0.481

Notes:

^*P<0.05 compared with before TACE. Data presented as mean ± standard deviation unless stated otherwise.

Abbreviations: DWI, diffusion-weighted imaging; PWI, perfusion-weighted imaging; HCC, hepatocellular carcinoma; TACE, transcatheter arterial chemoembolization; MTD, maximum tumor diameter; ADC, apparent diffusion coefficient; D_slow, slow ADC; D_fast, fast ADC; f, fraction of fast ADC; K^trans, transfer constant of vessel at the maximum level; K_ep, rate constant of backflux; V_e, extra-vascular space fractional volume.