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. 2016 Nov 14;9:7029–7037. doi: 10.2147/OTT.S112555

Table 3.

Comparisons of quantitative DWI and PWI parameters of HCC patients with different pathological types between the effective and ineffective groups before and after TACE

Parameter Primary liver cancer
P-value Gastric cancer metastasis
P-value Adenosquamous carcinoma
P-value
Effective
(n=38)		 Ineffective
(n=21)		 Effective
(n=16)		 Ineffective
(n=8)		 Effective
(n=13)		 Ineffective
(n=22)
MTD (cm)
 Before TACE 5.92±2.62 7.15±3.05 0.109 5.41±2.35 5.69±2.58 0.792 6.00±2.03 7.17±2.96 0.217
 After TACE 4.58±2.05 6.64±3.65 0.007 4.27±1.76 4.91±2.68 0.488 4.70±1.52 5.96±3.07 0.178
ADC (×10−3 mm2/s)
 Before TACE 1.01±0.33 0.71±0.06 <0.001 0.98±0.25 0.69±0.04 0.004 1.04±0.22 0.71±0.04 <0.001
 After TACE 1.32±0.17* 1.30±0.30* 0.744 1.31±0.13* 1.14±0.08* 0.003 1.34±0.11* 1.19±0.09* <0.001
Dslow (×10−3 mm2/s)
 Before TACE 0.75±0.18 0.57±0.16 <0.001 0.73±0.14 0.52±0.10 0.001 0.77±0.12 0.57±0.11 <0.001
 After TACE 0.97±0.19* 0.88±0.14* 0.062 0.95±0.15* 0.96±0.47* 0.938 0.99±0.13* 0.84±0.28* 0.079
Dfast (×10−3 mm2/s)
 Before TACE 32.96±10.51 45.00±11.99 <0.001 32.08±8.02 41.24±7.37 0.013 34.09±6.92 45.39±8.67 <0.001
 After TACE 21.74±7.79* 27.65±8.21* 0.008 20.97±6.14* 23.09±6.19* 0.435 22.51±5.30* 26.11±5.35* 0.062
f (%)
 Before TACE 15.09±5.38 15.78±6.18 0.656 14.57±4.23 13.84±3.80 0.685 15.63±3.65 15.98±4.47 0.813
 After TACE 14.72±4.39 15.09±5.14 0.772 14.35±3.35 13.48±3.16 0.724 15.19±2.90 15.26±3.72 0.954
Ktrans (/min)
 Before TACE 1.74±0.09 1.66±0.07 <0.001 1.73±0.07 1.64±0.04 0.003 1.75±0.06 1.66±0.05 <0.001
 After TACE 1.59±0.11* 1.64±0.18 0.190 1.58±0.09* 1.58±0.11 1.000 1.60±0.08* 1.64±0.13 0.325
Kep (/min)
 Before TACE 1.99±0.16 2.20±0.23 <0.001 1.98±0.12 2.13±0.14 0.012 2.01±0.10 2.21±0.17 <0.001
 After TACE 1.35±0.14* 1.51±0.41* 0.032 1.34±0.10* 1.60±0.36* 0.012 1.36±0.09* 1.45±0.47* 0.502
Ve
 Before TACE 0.45±0.07 0.44±0.06 0.583 0.45±0.05 0.42±0.04 0.155 0.46±0.04 0.44±0.04 0.162
 After TACE 0.43±0.08 0.42±0.10 0.676 0.42±0.06 0.39±0.06 0.261 0.44±0.05 0.43±0.07 0.655

Notes:

*

P<0.05 compared with before TACE. Data presented as mean ± standard deviation unless stated otherwise.

Abbreviations: DWI, diffusion-weighted imaging; PWI, perfusion-weighted imaging; HCC, hepatocellular carcinoma; TACE, transcatheter arterial chemoembolization; MTD, maximum tumor diameter; ADC, apparent diffusion coefficient; Dslow, slow ADC; Dfast, fast ADC; f, fraction of fast ADC; Ktrans, transfer constant of vessel at the maximum level; Kep, rate constant of backflux; Ve, extra-vascular space fractional volume.