Table 2.
Solubility of Triol in different BS/PC-MM systems with different weight ratios of BS to PC at a fixed total concentration
| BS/PC (w/w) |
Solubility of Triol (mg/mL)
|
|||||
|---|---|---|---|---|---|---|
| SGC/EPC | SGC/SPC | SDC/EPC | SDC/SPC | SBA-Na/EPC | SBA-Na/SPC | |
| 1:1 | 11.9±0.3 | 14.7±0.1 | 13.9±0.2 | 12.9±0.4 | 16.3±0.8 | 14.5±0.6 |
| 1.5:1 | 10.5±0.2 | 14.2±0.5 | 14.9±0.5 | 14.7±0.3 | 16.5±0.2 | 17.4±0.5 |
| 2:1 | 14.8±0.3 | 15.3±0.3 | 17.0±0.4 | 17.3±0.2 | 19.4±0.6 | 19.6±0.9 |
| 3:1 | 13.6±0.4 | 13.2±0.4 | 17.3±0.1 | 17.5±0.6 | 16.8±0.1 | 15.9±0.2 |
| 4:1 | 10.7±0.1 | 12.9±0.3 | 13.2±0.2 | 13.8±0.2 | 14.9±0.3 | 14.4±0.3 |
| 6:1 | 10.4±0.1 | 12.5±0.1 | 9.3±0.2 | 13.2±0.4 | 14.5±0.3 | 13.1±0.3 |
Notes: Total concentration of BS and PC was fixed at 100 mg/mL; data presented as mean ± SD (n=3).
Abbreviations: BS, bile salt; BS/PC-MM, bile salt/phosphatidylcholine mixed micelles; EPC, egg phosphatidylcholine; PC, phosphatidylcholine; SGC, sodium glycocholate; SPC, soya phosphatidylcholine; SDC, sodium deoxycholate; SBA-Na, swine bile acid-sodium salt; SD, standard deviation; Triol, Androst-3β,5α,6β-triol.