Table 4.
Stability of varied Triol-loaded BS/PC-MM systems at their optimized ratios and total concentrations at 25°C±2°C
| Triol-loaded BS/PC-MM systems | Appearance
|
||
|---|---|---|---|
| Month 0 | Month 1 | Month 3 | |
| SGC/EPC | − | − | − |
| SGC/SPC | − | − | − |
| SDC/EPC | − | − | + |
| SDC/SPC | − | − | + |
| SBA-Na/EPC | − | + | ++ |
| SBA-Na/SPC | − | + | ++ |
Notes: “−” indicates transparent; “+” indicates precipitation; “++” indicates severe precipitation.
Abbreviations: BS/PC-MM, bile salt/phosphatidylcholine mixed micelles; EPC, egg phosphatidylcholine; SBA-Na, swine bile acid-sodium salt; SDC, sodium deoxycholate; SGC, sodium glycocholate; SPC, soya phosphatidylcholine; Triol, Androst-3β,5α,6β-triol.