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. 2016 Nov 14;11:5671–5682. doi: 10.2147/IJN.S115357

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© 2016 Cui et al. This work is published and licensed by Dove Medical Press Limited

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Prussian blue staining of tumor tissues after intravenous injection of RGD-PAA-USPIO (A), plain USPIO (B), or RGD-PAA-USPIO plus free RGD peptides (C) and conventional HE staining (D) (×200).

Note: The arrow in the figures refer to the different iron particles of Prussian blue staining from RGD-PAA-USPIO(A), plain USPIO (B), and RGD-PAA-USPIO plus free RGD (C).

Abbreviations: HE, hematoxylin and eosin; PAA, polyacrylic acid; RGD, arginine-glycine-aspartic acid; USPIO, ultrasmall superparamagnetic iron oxide.