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. Author manuscript; available in PMC: 2017 Nov 17.
Published in final edited form as: Cell Chem Biol. 2016 Oct 20;23(11):1351–1361. doi: 10.1016/j.chembiol.2016.09.012

Figure 6. Strains Defective in Fe-S Cluster Assembly Are Sensitive to ’882.

Figure 6

(A) Aconitase activity is reduced in mutants lacking Fe-S cluster assembly factors when cultured in the presence of 50 μM ’882. *p < 0.05 by Student’s t test for each strain comparing DMSO with ’882.

(B) A LAC strain defective in Fe-S protein maturation is sensitive to 10 μM ’882 under microaerobic conditions in defined media lacking Ile and Leu. *p < 0.05 by Student’s t test for each time point comparing Δnfu ΔsufT + ‘882 with Δnfu ΔsufT + DMSO.

For (A) and (B), error bars represent SD combined from two independent experiments.