Figure 4.

Biocompatibility of blank micelles. *P<0.05; **P<0.01. (A) Micelles were tested on human aortic vascular smooth-muscle cells (T/G). The results suggested that the three-arm polymers had good biocompatibility. (B) RAW264.7 cells were cocultured with materials, with results indicating that the materials would not elicit an inflammatory response, thus further suggesting 3S-PLGA-PEG had good biocompatibility.

Abbreviations: 3S-PLGA, three-arm star block poly(lactic-co-glycolic acid); PEG, polyethylene glycol; NPs, nanoparticles; LPS, lipopolysaccharide; TNFα, tumor necrosis factor alpha; IL, interleukin.