Table 1. SNP rs numbers, alleles, allele frequencies, P-values, odds ratios and 95% confidence intervals (CIs) of odds ratios for SNPs associated with hypertension in the ADVANCE study with normal P-values ⩽5.00 × 10⁻² for male-only or female-only samples with CKD included and not included in the covariates for the analysis.

					Males				Females
SNP	Position chrome 13 (Build37/ hg19)	Coding allelea	Alternate allele	Frequency of coding allele	Association P-valueb	Odds ratio	Lower 95% CIc	Upper 95% CIc	Association P-value	Odds ratio	Lower 95% CIc	Upper 95% CIc
Without CKD as a covariate
rs9555251	107140587	T	C	0.35	2.23 × 10−3	0.78	0.66	0.91	8.77 × 10−1	0.98	0.78	1.24
rs7322914	107140910	T	C	0.35	2.19 × 10−3	0.78	0.66	0.91	8.69 × 10−1	0.98	0.78	1.23
rs7328698	107141349	C	G	0.35	1.88 × 10−3	0.77	0.66	0.91	8.02 × 10−1	0.97	0.77	1.22
rs7328882	107141433	A	G	0.35	1.13 × 10−3	0.76	0.65	0.90	8.78 × 10−1	0.98	0.78	1.23
rs7329357	107141705	A	G	0.35	1.73 × 10−3	0.77	0.65	0.91	8.62 × 10−1	0.98	0.78	1.23
rs9520087	107144320	A	G	0.43	9.35 × 10−3	0.81	0.69	0.95	7.69 × 10−1	1.03	0.83	1.29
With CKD as a covariate
rs9555251	107140587	T	C	0.35	4.62 × 10−3	0.79	0.67	0.93	6.29 × 10−1	0.94	0.74	1.20
rs7322914	107140910	T	C	0.35	4.57 × 10−3	0.79	0.67	0.93	6.21 × 10−1	0.94	0.74	1.19
rs7328698	107141349	C	G	0.35	4.12 × 10−3	0.79	0.67	0.93	5.60 × 10−1	0.93	0.74	1.18
rs7328882	107141433	A	G	0.35	2.54 × 10−3	0.78	0.66	0.91	6.27 × 10−1	0.94	0.75	1.19
rs7329357	107141705	A	G	0.35	3.91 × 10−3	0.78	0.66	0.92	6.99 × 10−1	0.95	0.76	1.21
rs9520087	107144320	A	G	0.43	1.78 × 10−2	0.82	0.70	0.97	9.03 × 10−1	1.01	0.81	1.28

^aCoding allele is reference allele for calculation of odds ratio. If odds ratio is <1, then coding allele is protective against hypertension.

^bP-values≤Bonferroni critical P-value of 3.33 × 10⁻³ are indicated in bold.

^c95% CI: 95% confidence interval for odds ratio.