Skip to main content
. 2016 Jul 6;24(12):1663–1670. doi: 10.1038/ejhg.2016.78

Figure 3.

Figure 3

Comparison of different types of MSX1 variants. In-frame versus truncating mutations and their accordingly phenotypes: non-syndromic tooth agenesis (ns TA) and non-syndromic orofacial clefts (ns OFC). In-frame (blue) versus truncating (red) variants and their accordingly number of missing teeth. All mutations in this histogram cause tooth agenesis with or without other phenotypes. The bars indicate the average number of missing teeth with error bars representing the maximum and minimum number. The arrows above the bars indicate the presence of other phenotypes. MSX1 variants affecting homeodomain (HD) versus not affecting HD with their accordingly phenotypes. Non-syndromic tooth agenesis (ns TA) and non-syndromic orofacial clefts (ns OFC). A full color version of this figure is available at the European Journal of Human Genetics journal online.