Table 2. Hematologic and non-hematologic toxicities (n = 574 patient-courses).
Grade 3 | Grade 4 | |||
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Toxicity | Patients (%) | Patient-courses (%) | Patients (%) | Patient-courses (%) |
Hematologic | ||||
Neutropenia | 10 (29%) | 75 (13%) | 18 (53%) | 29 (5%) |
Anemia | 2 (6%) | 3 (0.5%) | 0 | 0 |
Thrombocytopenia | 4 (12%) | 9 (1.6%) | 2 (6%) | 2 (0.3%) |
Non-hematologic | Patients (%) | Episodes | Patients (%) | Episodes |
| ||||
Infections | ||||
Pneumonia | 8 (24%) | 11 | 0 | 0 |
Fever | 3 (9%) | 3 | 0 | 0 |
Neutropenic fever | 3 (9%) | 3 | 0 | 0 |
Bacteremia | 1 (3%) | 1 | 1 (3%) | 1 |
Cellulitis | 2 (6%) | 2 | 0 | 0 |
Toxoplasmosis | 1 (3%) | 1 | 0 | 0 |
Parotitis | 1 (3%) | 1 | 0 | 0 |
Appendicitis | 1 (3%) | 1 | 0 | 0 |
| ||||
Other toxicities | ||||
VTE | 2 (6%) | 2 | 1 (3%) | 1 |
Dehydration | 1 (3%) | 1 | 0 | 0 |
Fatigue | 1 (3%) | 1 | 0 | 0 |
CHF exacerbation | 1 (3%) | 1 | 0 | 0 |
Atrial fibrillation | 1 (3%) | 0 | 0 | 0 |
Abbreviation: CHF, congestive heart failure.