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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Cell Biochem. 2016 Jun 21;118(1):15–25. doi: 10.1002/jcb.25617

Table 2.

mAbs that target the components of bone marrow microenvironment.

Target Antibody Phase Status Identifier
IL-6 Siltuximab II C NCT00911859
VEGF Bevacizumab II C N01-CM-62209
BAFF LY2127399 I C -
RANKL Denosumab III C NCT00330759
DKK1 BHQ880 I C NCT20050244
IL-6 Siltuximab II C NCT00911859

R: Recruiting; C: Completed; ONR: Ongoing, not recruiting; BAFF: B-cell activating factor;