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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: J Am Geriatr Soc. 2016 Oct 26;64(11):e189–e194. doi: 10.1111/jgs.14522

Table 2.

Example of reference values for 2 biomarkers.

NT-proBNP pg/mL
Men Women
age n 2.5th median 97.5th range n 2.5th median 97.5th range

<50 78 5 24 93.2 5 ; 115 105 10.2 54 414 5 ; 578
50–54 110 5 25 88.8 5 ; 183 151 7 46 158.2 5 ; 200
55–59 156 5 29 153.28 5 ; 844 216 11.3 53 234.7 5 ; 332
60–64 182 9 36 269.57 5 ; 1121 205 13.03 62 283.35 5 ; 684
65–69 132 6.55 55.5 791.67 5 ; 1570 134 16.65 80.5 286.9 5 ; 850
70–74 58 10.4 61.5 660.12 5 ; 693 58 35.85 120.5 400.45 19 ; 3650
75–79 32 16.77 103 1247.32 16 ; 1741 33 28.6 168 1110.4 19 ; 2812
80–84 25 56.8 150 1061.8 40 ; 1276 35 33.8 159 588.6 44 ; 4141
85–89 31 60.5 264 1112.25 50 ; 1263 35 51.65 213 701.1 53 ; 5244
90–94 77 75.4 341 3001.4 44 ; 3165 53 82.2 311 1904.8 72 ; 8398
95–99 40 75.7 315.5 2154.32 25 ; 2401 44 104.3 360 2251.67 32 ; 8837
100+ 9 287 644 3581.4 263 ; 3986 13 196.92 863 2449.17 79 ; 4307
SRAGE pg/mL
Men Women
age n 2.5th median 97.5th range n 2.5th median 97.5th range

<50 87 210.15 399 794.95 72 ; 1910 130 238.35 479 1082.97 234 ; 1796
50–54 126 189.5 415 831.12 166 ; 2256 205 224.27 472 1225.45 165 ; 3411
55–59 209 202.12 418.5 866.62 100 ; 2104 319 214.6 495 1251 134 ; 2959
60–64 248 193 414 998.75 127 ; 3198 312 208.45 512.5 1431.15 28 ; 2665
65–69 199 208.1 421.5 1120.17 178 ; 5992 233 214 490 1561.6 161 ; 4776
70–74 104 205.3 423 885.32 148 ; 1416 103 218.65 511 1224.8 186 ; 1853
75–79 50 242.57 455.5 1347.65 217 ; 1789 72 212.17 566.5 1208.75 174 ; 3669
80–84 57 209.6 545 1390.2 170 ; 1443 88 220.5 603 1819.75 145 ; 5714
85–89 73 240 541 1638.6 156 ; 2307 108 274.9 687.5 1879.77 209 ; 5214
90–94 175 265.4 695 1745.7 172 ; 4837 164 263.5 661 1680.05 229 ; 4439
95–99 104 254.28 689 1990.77 189 ; 7944 159 325.8 763.5 1871.75 213 ; 6314
100+ 13 307.1 727 2287.2 275 ; 2643 45 351.9 865 1784.47 245 ; 2864

The sample sizes per age groups vary because different diseases and treatment groups were found associated with nt-proBNP and SRAGE.