Table III. Somatic mutations in patients with dyskeratosis congenita.
| Patient ID | Sex | Age | Gene | Change Position (DNA, Protein) | WES Allele Frequency (%) | Clone size (%) |
|---|---|---|---|---|---|---|
| WUSTL-320.01 | M | 53 | TTN | c.10030C>T, p. Pro3298Ser | 33 | 66 |
| CHOP-9.01 | M | 16 | LPHN1 | c.1189G>A, p. Gly397Arg | 16 | 32 |
| CHOP-398.01 | M | 21 | DKC1 | c.-35A>G | 14 | 14 |
M, male; WES Allele Frequency, percent of WES reads containing the mutation; Clone size, WES Allele Frequency corrected for autosomal or X-linked status.