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Immunohistochemical staining demonstrated minimal IGF2R-staining intensity following treatment with 188Re-MEM-238 (A), moderate IGF2R-staining following treatment with 188Re-MOPC21 (B), and robust IGF2R-staining in both tumors treated with unlabeled MEM-238 (C) or in tumor untreated (D). Findings suggest that OS cells expressing IGF2R have been killed by the RIT treatment.
