Table 4.
Binding free energy change upon mutations (kcal/mol). Positive value indicates that the mutation decreases binding affinity. The most contradictory predictions are underlined and not used. The averaged prediction is shown in the last column.
BeAtMuSiC | SAAMBE | MutaBind | Average | |
---|---|---|---|---|
D87G | 1.65 | −0.54 | 0.42 | 1.04 |
D402Y | −0.22 | −0.66 | 0.18 | −0.23 |