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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: FEBS J. 2016 Oct 1;283(21):3898–3918. doi: 10.1111/febs.13895

Figure 8.

Figure 8

Gal/VNPT55 inhibits PC colony formation and downregulate protein expression of stem cell factors. Mnk1 knockdown exhibited similar effects. (a) PC-3 and DU145 were treated with gal/VNPT55 as indicated and stem cell factors analyzed by immunoblot. (b) 1000 cells/well (PC-3 and DU145), seeded in 6-well plates were treated with indicated concentrations of compounds for a period of 14 days. Media containing compounds were replaced every 3 days. Colonies were stained with 0.05% crystal violet. (c) Colonies from B were counted and presented as bar chart. Results are represented as averages from 3 separate experiments with S.E.M. (*p<0.5, **0.001).