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Ripples on spikes that are transformed to phasors can unambiguously lateralize the mesial temporal seizure onset zone. Coregistered CT-MRI of patient #4 with a left mesial temporal seizure onset zone; the rates of ripples on spikes are shown in blue (above), and the rate of the phase locked ripple phasors after transforming the ripples on spikes are shown in red (below). Dark gray macroelectrodes indicate contacts excluded due to poor recording quality.
