Table 1.
Single nucleotide polymorphism (SNP) details
| SNP ID | Common Name | SNP Type | HapMap-CEU* RAF |
Study RAF |
Location | Model |
|---|---|---|---|---|---|---|
| rs16944 | IL1B -511C>T | promoter | 0.36 | 0.33 | chr. 7 113594867 |
Recessive |
| rs1143634 | IL1B +3954C>T | coding; synonymous, exon 5 | 0.21 | 0.24 | chr. 7 113590390 |
Recessive |
| rs1800795 | IL6 -174G>C | promoter; MEF site | 0.47 | 0.41 | chr. 7 22766645 |
Dominant |
| rs10499563 | IL6 -6331T>C | promoter; Oct-1 binding site | 0.19 | 0.21 | chr. 7 22760488 |
Dominant |
RAF=Rare Allele Frequency in white, non-hispanics
*
Utah residents with Northern and Western European ancestry from the CEPH collection