Table 1.
Fluorescence in situ hybridization on enriched fetal samples (fcNIPT) and IPD karyotyping data in pregnant women with different aneuploidy risk levels
| Risk levels | Euploid | +21 | +18 | Triploidy | Total | |||
|---|---|---|---|---|---|---|---|---|
| Pregnancies | fcNIPT | IPD | fcNIPT | IPD | fcNIPT | IPD | ||
| Parental translocation | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| AMA | 23 | 1 | 1 | 0 | 0 | 0 | 0 | 24 |
| LR | 78 | 0 | 0 | 1 | 1 | 0 | 0 | 79 |
| IR | 36 | 1 | 1 | 0 | 0 | 1 | 1 | 38 |
| HR | 26 | 2a | 3 | 1 | 1 | 0 | 0 | 29 |
| Total | 165 | 4 | 5 | 2 | 2 | 1 | 1 | 172 |
AMA, advanced maternal age (≥35aa); LR, low risk (≤1:900); IR, intermediate risk (1:31/1:899); HR, high risk (≥1:30).
a
False negative fcNIPT result (trisomy 21 from rob(14;21)mat).