Table 3.

Subgroup analyses

		Calprotectin (μg/g)		Elastase (μg/g)		Alpha-1-antitrypsin (mg/g)
		Median (IQR)		Median (IQR)		Median (IQR)
Sex	Female	185 (97–264)	p = 0.15	444 (363–524)	p = 0.18	0.55 (0.31–0.80)	p = 0.37
	Male	130 (91–190)		362 (249–490)		0.43 (0.24–0.66)
PPI discontinued	≤7 days	191 (98–270)	p = 0.23	443 (341–519)	p = 0.95	0.58 (0.34–0.80)	p = 0.35
	>7 days	158 (79–237)		444 (332–530)		0.45 (0.23–0.81)
Cholecystectomy	Yes	193 (135–302)	p = 0.12	481 (350–545)	p = 0.18	0.60 (0.49–0.80)	p = 0.15
	No	162 (89–254)		435 (334–507)		0.48 (0.24–0.81)
Prior bariatric surgery	Yes	196 (115–304)	p = 0.41	515 (398–562)	p = 0.16	0.46 (0.31–0.72)	p = 0.58
	No	164 (93–256)		443 (333–510)		0.56 (0.30–0.81)
Any prior abdominal surgery	Yes	208 (89–270)	p = 0.54	464 (326–544)	p = 0.53	0.57 (0.36–0.80)	p = 0.31
	No	147 (106–234)		438 (342–490)		0.48 (0.20–0.81)

Data expressed in median and interquartile range (IQR). p value was calculated with Mann-Whitney U. p < 0.005 was considered statistically significant

PPI proton pump inhibitor, μg/g microgram per gram feces, mg/g milligram per gram dry feces