Table 1.
Pt No | Tumor No | Age | Initial Dx | Location of rec | Time to rec (mo) | CTV (cc) | Chemo for rec | Previous XRT | SBRT delivery | Total BED Gy10d | Local control | Survival | Grade 3/4 Tox | F/U (mo) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 58 | Ovarian-serous | PSW | 28 | 52.9 | No | No | CK only | 59.5 | LR | Death | No | 17 |
2 | 2 | 70 | Endometrial | Central | 19 | 29.1 | Yes | No | CK boost | 81.1 | LR | Death | No | 15 |
3 | 3 | 83 | Endometrial | PA | 15 | 32.8 | No | Yes | CK only | 35.7 | LC | Death | No | 6 |
4 | 4 | 82 | Endometrial | PA | 38 | 12.7 | Yes | No | CK only | 72 | LC | Alive | No | 92 |
5 | 5 | 80 | Cervical | PSW | 3 | 0.91 | No | No | CK boost | 112.8 | LC | Death | No | 19 |
6 | 6 | 40 | Cervical | Central | 28 | 9.4 | Yes | No | CK boost | 83.7 | LC | Alive | No | 24 |
7 | 7 | 72 | Cervical | Central | 78 | 29.8 | Yes | No | CK boost | 90.6 | LC | Alive | Noa | 45 |
8 | 8 | 82 | Cervical | Central | 507 | 285.3 | No | Yes | CK only | 48 | LC | Death | No | 5 |
9 | 9 | 68 | Ovarian-clear cell | PSW | 54 | 30 | No | No | CK only | 42.6 | LC | Death | No | 29 |
10 | 10 | 79 | Cervical | PSW | 15 | 68.3 | No | Yes | CK only | 48 | LC | Death | No | 7 |
11 | 11 | 37 | Cervical | Central | 29 | 88.8 | Yes | Yes | CK only | 37.5 | LC | Alive | Yesb | 21 |
12 | 12 | 64 | Endometrial | PSW | 18 | 8.3 | No | No | CK boost | 75.6 | LC | Alive | Noc | 77 |
13 | 13 | 72 | Endometrial | PA | 6 | 1.8 | No | No | CK boost | 81.1 | LC | Alive | No | 57 |
14 | 14 | 62 | Endometrial | PA | 3 | 30.7 | No | No | CK only | 37.5 | LC | Death | No | 63 |
– | 15 | 62 | Endometrial | PA | 3 | 8.4 | No | No | CK only | 37.5 | LC | Death | No | – |
15 | 16 | 71 | Cervical | PA | 10 | 8.3 | Yes | No | CK only | 65.6 | LC | Alive | No | 63 |
16 | 17 | 70 | Endometrial | PA | 5 | 103.5 | Yes | No | CK boost | 72.6 | LC | Alive | No | 60 |
– | 18 | 73 | Endometrial | PA | 45 | 7.7 | No | Yes | CK only | 65.6 | LC | Alive | No | – |
17 | 19 | 76 | Carcinosarcoma | Central | 14 | 14.9 | No | Yes | CK only | 59.5 | LR | Alive | No | 23 |
18 | 20 | 80 | Endometrial | Central | 10 | 85.7 | Yes | Yes | CK only | 37.5 | LC | Death | No | 11 |
19 | 21 | 80 | Cervical | Central | 34 | 8.3 | – | No | CK boost | 98 | LC | Alive | No | 8 |
20 | 22 | 89 | Uterine-serous | PA | 34 | 24 | No | No | CK only | 72 | LR | Death | No | 16 |
– | 23 | 89 | Uterine-serous | PA | 38 | 8.7 | No | No | CK only | 48 | LR | Death | No | – |
21 | 24 | 65 | Carcinosarcoma | PA | 35 | 31.2 | Yes | No | CK only | 37.5 | LC | Alive | No | 22 |
22 | 25 | 60 | Uterine-serous | Central | 47 | 50 | No | Yes | CK only | 48 | LR | Death | No | 14 |
– | 26 | 60 | Uterine-serous | Central | 47 | 11.4 | No | Yes | CK only | 48 | LR | Death | No | – |
23 | 27 | 89 | Endometrial | PSW | 229 | 38.4 | No | Yes | CK only | 72 | LC | Death | No | 43 |
24 | 28 | 79 | Endometrial | Central | 25 | 15.7 | No | Yes | CK only | 59.5 | LR | Alive | No | 29 |
25 | 29 | 66 | Ovarian-serous | PSW | 80 | 4.7 | Yes | No | CK only | 48 | LR | Alive | No | 47 |
26 | 30 | 59 | Endometrial | PSW | 153 | 43.6 | Yes | No | CK boost | 81.1 | LC | Alive | No | 64 |
27 | 31 | 52 | Cervical | PSW | 3 | 36.7 | No | Yes | CK only | 43.2 | LC | Death | No | 59 |
– | 32 | 52 | Cervical | PSW | 3 | 36.7 | No | Yes | CK only | 43.2 | LC | Death | No | – |
28 | 33 | 56 | Cervical | PA | 30 | 67.3 | Yes | Yes | CK only | 53.6 | LC | Alive | No | 17 |
29 | 34 | 60 | Endometrial | PSW | 98 | 86.5 | Yes | Yes | CK only | 48 | LC | Alive | No | 10 |
30 | 35 | 66 | Cervical | PA | 21 | 7.9 | No | No | CK only | 48 | LC | Death | No | 26 |
Pt, patient; No, number; Dx, diagnosis; rec, recurrence; mo, months; CTV, clinical target volume; cc, cubic centimeters; Chemo, chemotherapy; BED, biological equivalent dose; XRT, radiotherapy; Tox, toxicity; PA, para-aortic; PSW, pelvic sidewall; CK, cyberknife; LC, local control; LR, local recurrence; F/U, follow-up.
aGrade 2 radiation cystitis.
bGrade 3 rectovaginal/vaginovesicular fistulas.
cGrade 2 proctitis.
dIncludes all radiation delivered for recurrence which includes SBRT alone dose or external beam + SBRT combined doses if boost used.
–, unknown if chemotherapy delivered.