Table 2.

Response of resting measures of metabolic and cardiovascular function to exercise training and hematocrit normalization

Parameter	UN30	TR30	UN42	TR42	Main Effect Hct	Main Effect Training	Interaction
Hct, %	31.4±1.7	30.9±3.9	41.5±2.1	42.1±2.4	<0.0001	0.92	0.28
Hemoglobin, g/dl	10.7±0.8	10.5±1.3	14.4±0.9	14.6±1.0	<0.001	0.99	0.31
RBC volume, ml/kg	17.7±2.9	17.6±3.3	24.4±3.9	25.3±4.9	<0.0001	0.59	0.50
Plasma volume, ml/kg	46.3±8.5	46.8±8.1	42.3±6.2	43.3±8.7	0.016	0.624	0.87
Blood volume, ml/kg	64.0±11.2	64.3±10.4	66.6±9.7	68.6±13.3	0.113	0.596	0.69
VO2, ml/kg per min	3.0±0.6	2.8±0.5	3.1±0.6	3.0±0.6	0.179	0.179	0.65
Cardiac output, L/min	7.4±1.8	7.3±2.0	7.5±2.1	7.3±1.9	0.89	0.69	0.89
Heart rate, bpm	73±9	77±12	72±12	73±12	0.25	0.25	0.49
a-vO2 difference, vol%	3.2±0.6	3.2±0.7	3.4±0.9	3.4±1.0	0.20	0.99	0.99
aO2, vol%	14.3±1.2	14.2±1.9	18.6±1.6	18.8±1.9	<0.0001	0.88	0.64
Resting systolic BP, mmHg	145±21	142±22	146±23	140±21	0.90	0.28	0.72
Resting diastolic BP, mmHg	84±13	83±12	90±15	87±11	0.045	0.42	0.686
Resting MAP, mmHg	104±12	103±13	109±15	104±11	0.23	0.23	0.42

Data are presented as means±SDs for a given variable at a given time point. Hct, hematocrit; RBC, red blood cell; a-vO₂ difference, arteriovenous oxygen difference; aO₂, arterial oxygen content.