Table 5.

Effects of intradialytic training and hematocrit normalization on skeletal muscle strength, structure, and function

Parameter	UN30	TR30	UN42	TR42	Main Effect Hct	Main Effect Training	Interaction
Type 1 fiber, %	33±10	32±9	31±9	29±9	0.16	0.40	0.78
Area type 1, μm2	5366±1955	5226±1757	5171±1575	5140±1665	0.68	0.80	0.87
Area type 2, μm2	3528±1498	3364±1106	3393±1168	3260±1062	0.61	0.53	0.95
Capillary density, μm2	271±85	280±103	268±145	270±142	0.78	0.81	0.88
Capillary-to-fiber ratio	1.1±0.5	1.2±0.6	1.1±0.7	1.0±0.7	0.99	0.99	0.99
Citrate synthase, μm/min per dry gram	12.6±4.8	18.0±7.2	12.2±4.7	17.9±7.5	0.83	<0.0001	0.90
HAD, μm/min per dry gram	25.8±8.2	30.0±14.7	22.8±7.5	30.6±12.9	0.58	0.0066	0.41
Phosphofructokinase, μm/min per dry gram	87.2±50.2	74.1±34.0	86.4±50.3	97.7±64.5	0.25	0.93	0.22
Buffer capacity, μm H+ per pH per dry gram	356±89	387±85	359±71	361±79	0.46	0.29	0.36
Myoglobin, ng/wet g	2.3±0.7	2.0±0.7	2.4±0.9	2.3±0.7	0.17	0.17	0.49

Data are presented as means±SDs for a given variable at a given time point. Hct, hematocrit; H⁺, hydrogen ions.