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. 2016 Nov 8;2016:9859021. doi: 10.1155/2016/9859021

Table 2.

Glutathione (GSH) pathway genes.

Study Sample (number) Genes Description
Chiong et al. [21] 99 hGPX1(198 C/T) It was associated with an increased recurrence risk (HR = 3.0; p = 0.03)
Kang et al. [23] 135 GSTT1-positive It had a higher risk of BCG nonresponsiveness (HR = 14; p = 0.022)
Ke et al. [22] 191 GSS(rs7265992 A/A)
GSS(rs6060124 A/A)
GSS(rs4911455 C/C)
GPX2(rs10133290 C/C)
GSTM4(rs560018 G/G)
They were associated with an elevated risk of recurrence
Ke et al. [22] 191 GPX5(rs377514 C/C)
GSTM3(rs4970737 G/G)
They demonstrated protective association