Table 3.
Results of BQTN analyses for potential combinatorial associations of SLC30A8-related SNPS with T2D-related traits.
| Characteristic | eT2D | iT2D | FG | FI | 2hG | 2hI | HOMA-IR | HOMA-β |
|---|---|---|---|---|---|---|---|---|
| h r 2 | 0.65 | 0.66 | 0.42 | 0.42 | 0.37 | 0.32 | 0.40 | 0.26 |
| BIC of best model compared to the null model |
0.00 | 0.00 | 0.00 | −0.34 | 0.00 | 0.00 | −1.75 | −1.49 |
| Number of models in window | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
| SNPS in the best model (p) | ||||||||
| rs2938864 | — | — | −0.06 | — | — | −0.08 | — | |
| (0.54) | (0.71) | |||||||
| rs1001646 | — | — | — | — | — | — | — | — |
| rs7817754 | — | — | — | — | — | — | — | — |
| rs2047962 | — | — | — | — | — | — | — | — |
| rs6469668 | — | — | — | — | — | — | — | 0.07 |
| (0.68) | ||||||||
| rs6469667 | — | — | — | — | — | — | — | — |
| rs7832958 | — | — | — | — | — | — | — | — |
| rs6469674 | — | — | — | — | — | — | — | — |
| rs13269857 | — | — | — | — | — | — | — | — |
| rs3020106 | — | — | — | — | — | — | — | — |
| rs3020119 | — | — | — | — | — | — | — | — |
eT2D, ever T2D; iT2D, incident T2D; FG, fasting glucose; FI, fasting insulin; 2hG, 2-hour glucose; 2hI, 2-hour insulin; BIC, Bayesian information criterion.