Table 1.
Detection of excised MDA-MB-231 tumors through simulated breast tissue phantoms.a
| Contrast agent | Time (h) | Phantom Thickness (mm) | |||||
|---|---|---|---|---|---|---|---|
| 0 | 2 | 3 | 4 | 5 | 6 | ||
| ICG | 4 | +++ | ++ | + | - | - | - |
| 24 | + | - | - | - | - | - | |
| 72 | ++ | + | - | - | - | - | |
| NanoICGPBA | 4 | ++ | + | - | - | - | - |
| 24 | ++ | + | - | - | - | - | |
| 72 | +++ | ++ | - | - | - | - | |
| NanoICG5βCA | 4 | ++ | + | - | - | - | - |
| 24 | ++ | + | - | - | - | - | |
| 72 | ++ | + | - | - | - | - | |
| Cy7.5 | 4 | + | - | - | - | - | - |
| 24 | ++ | + | - | - | - | - | |
| 72 | ++ | + | - | - | - | - | |
| NanoCy7.510-Ø | 4 | +++ | +++ | ++ | + | - | - |
| 24 | +++ | +++ | ++ | + | - | - | |
| 72 | +++ | ++ | + | - | - | - | |
| NanoCy7.510-L | 4 | +++ | +++ | ++ | + | - | - |
| 24 | +++ | +++ | ++ | + | - | - | |
| 72 | +++ | +++ | ++ | + | - | - | |
| NanoCy7.510-H | 4 | +++ | +++ | ++ | + | - | - |
| 24 | +++ | ++ | + | - | - | - | |
| 72 | +++ | ++ | + | - | - | - | |
| NanoCy7.5100-Ø | 4 | +++ | ++ | + | - | - | - |
| 24 | +++ | + | - | - | - | - | |
| 72 | +++ | ++ | + | - | - | - | |
| NanoCy7.5100-L | 4 | +++ | +++ | +++ | +++ | ++ | + |
| 24 | +++ | ++ | ++ | + | - | - | |
| 72 | +++ | ++ | + | - | - | - | |
| NanoCy7.5100-H | 4 | +++ | +++ | ++ | + | - | - |
| 24 | +++ | +++ | ++ | + | - | - | |
| 72 | +++ | ++ | + | - | - | - | |
aLaser power set to 30 mW; distance between phantom material and laser tip was 1 cm.