Figure 5.

Survival of NCI-H460 cells after chemo- and photodynamic combined therapy: (A) Chemotherapy and photodynamic therapy of the nanoparticles with 633 nm laser. (B) Detection of photodamage of ZnPc/CPT-TPPNPs by fluorescence microscopy using fluorescent probes (double-staining with PI and calcein-AM). Dead cells: red fluorescence of PI; living cells: green fluorescence of calcein-AM. The left side of the dotted line was irradiated with the laser while the right side was in the dark. The data are shown as mean±SD (n =4), * indicates P< 0.05.