Figure 14.
(A) Molar extinction spectra of BphP1 in the ON-state (Pfr) and OFF-state (Pr). (B) In vivo PA images of a nude mouse at 1 week after injection of BphP1-expressing tumor cells. (C) Normalized PA signal profiles along the white dashed line in B. (D) An overlay of the tumor (in color) and the blood-dominated OFF-state image (in grayscale). Hb: hemoglobin. Reproduced with permission 149. Copyright 2016 Nature. (E) Illustration showing the structure of MNP-Au and principle of mmPAI. (F) Conventional PAI and mmPAI of Au NR, MNP-Au and MNP. Reproduced with permission 150. Copyright 2010 Macmillan Publishers Limited.