Figure 3.

Examples of image-guided interstitial PDT for deeply situated tumors. A. Photograph of surgeon inserting needles under ultrasound-guidance for placing fibers in deep tissue. B. Light delivered to the heamangioma of the left infraorbital region through multiple fibers. Photographs of solid skin tumor in the ear with 6 fibers implanted under ultrasound guidance. C. One fiber is used for illumination while other 5 fibers are used for diagnostic purposes to evaluate light fluence, sensitizer concentration and tissue oxygenation. D. All the fibers are used in “transmit” mode to illuminate the whole tumor for PDT. Images adapted with permission from Jerjes et al ¹⁸ and Svanberg et al. ²¹