Table 3.
Haplotype analysis using three markers from OXTR.
| Phenotype | Markers | Haplotype | p-value | Z | ||||
|---|---|---|---|---|---|---|---|---|
| ASD | rs2254298 | rs2268493 | A | T | 0.026 | 2.23 | ||
| ADOS−-Social affect | rs53576 | rs2254298 | rs2268493 | G | A | T | 0.008 | 2.63 |
| rs53576 | rs2254298 | G | A | 0.017 | 2.40 | |||
| rs2254298 | rs2268493 | A | T | 0.016 | 2.41 | |||
| ABC−-Social withdrawal | rs53576 | rs2254298 | rs2268493 | G | G | C | 0.009 | −2.59 |
| rs53576 | rs2268493 | G | C | 0.009 | −2.62 | |||
| rs2254298 | rs2268493 | A | T | 0.036 | 2.10 | |||
| ADOS−-RRB | rs53576 | rs2254298 | rs2268493 | A | G | C | 0.032 | −2.15 |
| rs53576 | rs2268493 | A | C | 0.024 | −2.25 | |||
Haplotypes were created from three SNPs (rs53576, rs2254298, and rs2268493) previously associated with ASD. Data were analyzed for associations with ASD diagnosis and subphenotypes.