TABLE 2.

Pharmacological parameters of results shown in Fig. 3, A–C

Top and bottom are expressed as fold of basal, and log EC₅₀ is expressed as logged EC₅₀ (M).

	ZnCl2
	316 μM (N = 4)	100 μM (N = 4)	31.6 μM (N = 4)	0 μM (N = 4)
GPR39-C3
Top	2.59 ± 0.06	3.21 ± 0.08	2.87 ± 0.08	3.07 ± 0.10
Bottom	1.40 ± 0.09	1.18 ± 0.11	0.96 ± 0.10	1.00 ± 0.10
Log EC50	−8.49 ± 0.13	−8.48 ± 0.10	−8.16 ± 0.11	−8.00 ± 0.12
Hill slope	1.29 ± 0.46	1.20 ± 0.30	1.18 ± 0.30	0.94 ± 0.23
LY2784544
Top	3.40 ± 0.38	3.94 ± 0.30	4.57 ± 0.12	4.41 ± 0.07
Bottom	1.92 ± 0.07	1.31 ± 0.11	1.07 ± 0.22	1.00 ± 0.22
Log EC50	−9.36 ± 0.14	−8.51 ± 0.14	−6.98 ± 0.16	−6.35 ± 0.19
Hill slope	1.30 ± 0.18	0.63 ± 0.17	0.79 ± 0.15	0.94 ± 0.59
GSK2636771
Top	3.47 ± 0.09	3.68 ± 0.12	3.75 ± 0.27	3.68 ± 0.63
Bottom	1.91 ± 0.15	1.36 ± 0.12	1.08 ± 0.08	1.01 ± 0.05
Log EC50	−8.60 ± 0.18	−7.97 ± 0.13	−6.67 ± 0.14	−5.99 ± 0.25
Hill slope	1.01 ± 0.38	0.86 ± 0.20	1.01 ± 0.25	1.01 ± 0.28