TABLE 5.
Measured mEPSC characteristics of neurons from P7–14 mice
| AMPAR Time Constant (ms) | NMDAR Time Constant (ms) | AMPAR Amplitude (pA) | NMDAR Amplitude (pA)a | mEPSC Detection rate (s−1) | AMPAR/NMDAR ratiob | n | |
|---|---|---|---|---|---|---|---|
| Interneuron WT | 4.6 ± 0.5 | 138 ± 37 | 20 ± 1.6 | 2.1 ± 0.2 | 1.6 ± 0.4 | 9.7 ± 1.1 | 25 |
| Interneuron Grin2d−/− | 3.9 ± 0.7 | 140 ± 48 | 24 ± 4.3 | 3.9 ± 1.3 | 1.0 ± 0.5 | 6.8 ± 0.7 | 4 |
| Pyramidal WT | 6.5 ± 0.4 | 91 ± 8.6 | 21 ± 1.4 | 4.7 ± 0.6 | 0.92 ± 0.22 | 5.9 ± 0.9 | 17 |
a
NMDAR amplitude is calculated from the amplitude of slower component of the dual exponential fit.
b
Recordings were performed in 0.1 mM Mg2+. Values are mean ± S.E.M.; n is the number of cells.