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. 2016 Sep 27;7(14):1968–1978. doi: 10.7150/jca.14634

Table 4.

The research on the integration between cancer treatments and palliative cares (PART C).

N. respondents %
C1 Do you consider it to be the competence of medical oncologists to activate or participate in clinical trials dealing with treatment of symptoms in cancer patients?
Completely agree 286 74
Partially agree 99 25
Disagree 4 1
I don't know 0 0
C2 Do you think there may be ethical or psychological issues in giving information and consenting for clinical trials aimed at improving treatment of symptoms?
No 351 89
Yes (specify§§) 14 4
I don't know 26 7
C3 Which areas of palliative medicine do you consider important for medical oncologists to invest in research?
Communication and relational aspects 228 24* 51^
Treatment of symptoms 231 24 51
Organization and management models 191 20 67
Interrelation between oncological treatment and palliative care 300 32 26
None of the above 3 0 1
C4 What do you think should be the principal objective of clinical research in patients with advanced non-curable cancer?
Improvement in overall survival 58 15
Improvement in disease free survival 15 4
Improvement in quality of life 304 77
Cost reduction 0 0
Other 14 4
C5 Which is the definition of “clinical benefit” you consider most appropriate?
Gain in disease-free survival 22 5
Dimensional decrease of tumor 4 1
Improvement in quality of life 342 88
Pain reduction 5 2
Other 18 4
C6 In the choice of a palliative/symptomatic treatment of the oncological patient you rely on:
Experience 174 45
Advice of an expert in Palliative Care 104 26
Consultation of guidelines 87 22
Patients and their families 8 2
Other 18 4
C7 With regard to the trial by Temel et al (4), which are your considerations:
The results are applicable only to NSCLC 37 9
The results may be replicated in all tumor types 221 57
Such results should change the practice in medical oncology 116 29
Such results do not change the practice in medical oncology 17 5

Footnotes: * % on total options; ^ % on single options

§§ Positive bias for expectations; patients' awareness; difficulty in communication; difficulty in randomization; patients' cultural-background difficulties; should be palliative specialists' task; it's part of the oncologist's tasks; side effects and effective improvement of prognosis; overt and punctual communication of prognosis and difficulties of such disclosures to be accepted by EC; ethics problems in placebo use in terminally ill patients; patients' may associate palliative care use with terminal care; symptoms' care is usually felt as a “non-therapy” when it is the sole therapy used; fear of receiving “less-curative” treatment; poor understanding; fear of obtaining a consensus which is ethically valid for patients in poor general conditions; palliative sedation.