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Focal immunohistochemical reactivity for synaptophysin (SYP) and ASCL1 in neuroepithelial bodies (NEBs). NEBs (arrows) visibly protrude into lung airway lumen (Lu) and tend to be larger in NNK-treated animals. Sections were stained using a standard avidin-biotin complex (ABC) method with peroxidase and DAB, followed by counterstaining with light green SF. Scale bar: 100 µm.
