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. 2016 Nov 22;6:37502. doi: 10.1038/srep37502

Table 1. EC50 values for inhibition of sorbitol-mediated lysis (NPP activity) and growth of P. falciparum blood stage parasites treated with the compounds indicated.

  EC50 for Sorbitol Lysis EC50 for Parasite Growth
NPPB 1.23 μM 62.6 μM
(1.1–1.4) (49–80)
Furosemide 11.8 μM 134 μM
(10–14) (120–150)
MMV020439 222 nM 329 nM
(170–280) (280–390)
MMV007571 367 nM 857 nM
(310–440) (720–1000)

The EC50 values (in bold) were calculated from the pooled data from three independent replicates of three technical replicates each. 95% confidence intervals are listed in parenthesis.