. 2016 Oct 18;13(11):825–834. doi: 10.7150/ijms.16185

Table 2.

The association between individual benzodiazepine use and dementia based on the FAERS database.

	Cases	Non-cases	ROR	95% CI	IC	95% CI
Benzodiazepines	50,302	1,001,070	1.63	1.61-1.64	0.66	0.65-0.67
Short-acting	800	18,637	1.38	1.28-1.48	0.44	0.34-0.55
Etizolam	691	16,019	1.38	1.28-1.49	0.45	0.34-0.56
Clotiazepam	107	2,597	1.32	1.09-1.60	0.38	0.10-0.67
Flutazolam	2	21	3.05	0.72-13.01	0.80	-0.97-2.56

Medium-acting	35,772	739,016	1.56	1.54-1.58	0.61	0.59-0.62
Lorazepam	16,245	327959	1.59	1.57-1.62	0.64	0.62-0.66
Alprazolam	18,075	384,519	1.51	1.49-1.53	0.57	0.55-0.59
Fludiazepam	3	279	0.34	0.11-1.07	-1.26	-2.71-0.20
Bromazepam	1,444	26,161	1.77	1.68-1.87	0.79	0.71-0.87
Nimetazepam	5	98	1.63	0.67-4.02	0.53	-0.68-1.74

Long-acting	13,186	233,750	1.81	1.78-1.85	0.82	0.79-0.84
Diazepam	11,267	195,417	1.85	1.82-1.89	0.85	0.82-0.88
Cloxazolam	200	3,084	2.08	1.80-2.40	1.00	0.79-1.21
Chlordiazepoxide	740	17,880	1.33	1.23-1.43	0.39	0.28-0.50
Medazepam	15	220	2.18	1.29-3.69	0.97	0.23-1.72
Clorazepate	964	17,149	1.80	1.69-1.92	0.81	0.72-0.91

Ultra-long-acting	544	9,667	1.80	1.65-1.97	0.81	0.69-0.94
Flutoprazepam	6	161	1.19	0.53-2.70	0.20	-0.91-1.32
Loflazepate	185	3,483	1.70	1.47-1.97	0.73	0.51-0.95
Mexazolam	7	182	1.23	0.58-2.62	0.24	-0.80-1.29
Oxazolam	18	294	1.96	1.22-3.16	0.86	0.18-1.54