TABLE 1.
Body weight, energy efficiency, and plasma and liver characteristics of male mice fed a 45%-fat diet with or without an ETWB supplement for 10 wk1
| Variable | Control | ETWB | P2 |
| Terminal body weight, g | 34.5 ± 0.69 | 31.1 ± 0.39 | 0.0003 |
| Adiposity index3 | 3.15 ± 0.17 | 2.37 ± 0.11 | 0.0007 |
| Cumulative energy intake,4 kcal/10 wk | 743 ± 14 | 687 ± 12 | 0.0044 |
| Cumulative energy intake, kcal/g terminal body weight | 21.9 ± 0.4 | 22.5 ± 0.5 | 0.32 |
| Feed efficiency,4 mg body weight gained/total kcal consumed | 22.7 ± 0.7 | 20.1 ± 0.7 | 0.0133 |
| Plasma glucose, mg/dL | 138 ± 4.9 | 154 ± 10 | 0.09 |
| Plasma insulin, ng/mL | 0.60 ± 0.06 | 0.62 ± 0.06 | 0.79 |
| Plasma NEFAs, mM | 0.24 ± 0.01 | 0.24 ± 0.01 | 0.65 |
| Plasma TGs, mg/dL | 52.6 ± 2.5 | 46.5 ± 3.6 | 0.18 |
| Liver weight, g | 1.19 ± 0.03 | 1.18 ± 0.01 | 0.74 |
| Liver, % of body weight | 3.44 ± 0.06 | 3.80 ± 0.06 | 0.0003 |
| Liver TGs, mg/g | 46.7 ± 3.0 | 35.0 ± 1.1 | 0.0009 |
| Liver ROS, mmol DCF · mg protein−1 · min−1 | 3.44 ± 0.21 | 4.58 ± 0.29 | 0.0035 |
1
Values are means ± SEMs, n = 15/group. DCF, dichlorofluorescein; ETWB, enzyme-treated wheat bran; NEFA, nonesterified fatty acid; ROS, reactive oxygen species.
2
Derived by using 2-tailed Student’s t test. P < 0.05 was considered significant.
3
Adiposity index is the sum of epididymal, retroperitoneal, and subcutaneous fat pads in grams. Samples were collected from mice in the postabsorptive state after ∼4–8 h food deprivation in the morning.
4
To convert kcal to kJ, multiply by 4.184.