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. 2016 Nov 22;6:37370. doi: 10.1038/srep37370

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Both the osteo group and LED + osteo group demonstrated increased OPN mRNA expression. OPN mRNA expression in the LED + osteo group was significantly higher than those of the control group, LED group and osteo group (p < 0.05).