Table 1.
Baseline characteristics of subjects in lung cancer group and healthy control group case: 684; control: 602
| No. of cases (%) | No. of controls (%) | Allele frequency | ||
|---|---|---|---|---|
| χ 2 | P | |||
| Gender | ||||
| Male | 498 (72.8) | 400 (66.5) | 0.703 | 0.402 |
| Female | 186 (28.2) | 202 (33.5) | ||
| Age (x ± s) | 56.1 ± 11.3 | 57.1 ± 10.0 | 1.306 | 0.192 |
| <60 | 408 (59.7) | 328 (54.5) | 2.006 | 0.157 |
| ≥60 | 276 (40.3) | 274 (45.5) | ||
| Smoking status | ||||
| Smokers | 458 (66.9) | 268 (44.6) | 37.461 | 0.001 |
| Non-smokers | 226 (33.1) | 334 (55.4) | ||
| Pathological type | ||||
| SCC | 221 (32.3) | – | ||
| AC | 257 (37.6) | – | ||
| ASC | 64 (9.4) | – | ||
| SCLC | 142 (20.8) | – | ||
| TNM staging | ||||
| I | 239 (34.9) | – | ||
| II | 181 (26.5) | – | ||
| III | 235 (34.4) | – | ||
| IV | 29 (4.2) | – | ||
| T2437A allele | ||||
| T | 559 (69.2) | 497 (70.6) | 0.357 | 0.550 |
| A | 249 (30.8) | 207 (29.4) | ||
| C149T | ||||
| C | 619 (76.6) | 559 (79.4) | 1.707 | 0.191 |
| A | 189 (23.4) | 145 (20.6) | ||
SCC squamous cell carcinoma, AC adenomatous carcinoma, ASC adenosquamous carcinomas, SCLC small cell lung cancer, TNM tumor-node-metastasis