Table 3.
Severity of microscopic lesions and presence of PEDV antigen determined by IHC in tissues from pigs infected with PEDV at 8 weeks of age
| Segmenta | dpi 1 | dpi 2 | dpi 3 | dpi 14 | ||||
|---|---|---|---|---|---|---|---|---|
| Lesionsb | PEDVc | Lesions | PEDV | Lesions | PEDV | Lesions | PEDV | |
| Duodenum | 0/5 | 0/5 | 0/3 | 1/3 (3, 1)d | 13/20 (2, 1) | 15/20 (3, 2.3) | 0/30 | 0/30 |
| Ileum | 0/5 | 0/5 | 0/3 | 1/3 (3, 1) | 13/20 (3, 2) | 15/20 (3, 3) | 0/30 | 0/30 |
| Jejunum | 0/5 | 0/5 | 0/3 | 1/3 (1, 0.3) | 13/20 (3, 3) | 15/20 (3, 3) | 0/30 | 0/30 |
| Colon | 0/5 | 0/5 | 0/3 | 0 | 0/20 | 6/20 (1, 0.3) | 0/30 | 0/30 |
| Mesenteric lymph node | 0/5 | 0/5 | 0/3 | 0/3 | 0/20 | 12/20 (2, 1) | 0/30 | 0/30 |
aThree sections were collected and evaluated for each intestinal segment.
bMicroscopic lesions included villous atrophy and lymphocytic inflammation and were scored as 0 = absent to 3 = severe.
cPrevalence and amount of PEDV antigen were scored as 0 = absent to 3 = abundant for each intestinal segment.
dThe average score of three sections of each segment was calculated as the segment score. Data presented as prevalence (highest score in a segment, median segment score).