TABLE 2.
Summary of Adverse Events (>10% in All Patients, Based on 54 pts)
| Total | ||||
|---|---|---|---|---|
| (N = 54) | ||||
| All Grade | Grade 3, 4, or 5 | |||
| Event | n (%) | n (%) | ||
| Abnormal electrolytes | 25 | 46.3 | 3 | 5.6 |
| Constitutional symptoms | 24 | 44.4 | 3 | 5.6 |
| Diarrhea | 23 | 42.6 | 0 | 0 |
| Elevated Alk phos | 21 | 38.9 | 2 | 3.7 |
| Abnormal liver enzymes | 19 | 35.2 | 2 | 3.7 |
| Hypertension | 18 | 33.3 | 7 | 13 |
| Rash | 17 | 31.5 | 1 | 1.9 |
| Anorexia | 15 | 27.8 | 2 | 3.7 |
| Hyperglycemia | 15 | 27.8 | 0 | 0 |
| Pain | 15 | 27.8 | 1 | 1.9 |
| Proteinuria | 14 | 25.9 | 0 | 0 |
| GI complaint | 13 | 24.1 | 1 | 1.9 |
| Infection | 13 | 24.1 | 2 | 3.7 |
| Renal insufficiency | 12 | 22.2 | 0 | 0 |
| Anemia | 11 | 20.4 | 0 | 0 |
| Pulmonary | 11 | 20.4 | 3 | 5.6 |
| Bleed | 10 | 18.5 | 0 | 0 |
| Hypoalbuminemia | 7 | 13 | 1 | 1.9 |