Skip to main content
. Author manuscript; available in PMC: 2016 Nov 22.
Published in final edited form as: Free Radic Biol Med. 2014 Dec 12;80:158–163. doi: 10.1016/j.freeradbiomed.2014.12.006

Scheme 1. Reactions of potein thiyl radicals considered in the kinetic simulations.

Scheme 1

Abbreviations used:

HAsc−, ascorbate; HAsc•−, ascorbyl radical; HRSH, intact protein; HDRSH, protein with incorporated D-Cys; HRS−, protein thiolate; HRS•, protein thiyl radical; •βRSH, alpha-mercaptoalkyl radical of protein; •αRSH, backbone radical of protein at Cys; •OOαRSH, backbone peroxyl radical; HRS-OO•, oxygen adduct to a protein thiyl radical; HRSO2•, protein sulfenyl radical; HGSH, Glutathione; HGS•, Glutathione thiyl radical; #, This intermediate is invoked by analogy to known chemistry