FIG. 1.

Stat3-GFP expression in the developing nervous system and in the adult regenerating retina. (A) A schematic representation of the gfat:stat3-gfp transgene construct. (B) Stat3-GFP is expressed throughout the brain and spinal cord in live larva. (C) Expression of Stat3-GFP in glutamine synthetase (GS)-positive Müller glia at 4 days postfertilization (dpf). (D) Stat3-GFP is not detectable in uninjured adult retina but expressed in Müller glia at an injury site in the inner nuclear layer (INL) at 4 days postretinal injury (dpi). The asterisk marks the injury site. (E) Colocalization of Stat3-GFP, p-Stat3, BrdU in Müller glia-derived progenitors. Scale bar 20 μm (C), 50 μm (D, E). Color images available online at www.liebertpub.com/zeb