Table 2.
Health-related quality of life (SF-36 domains) in the vitamin D group and the placebo group (n = 187).
Δ Vitamin D group (n = 94) | Δ Placebo group (n = 93) | β* | B* | 95% CI | P | |
---|---|---|---|---|---|---|
Physical functioning | −0.55 ± 12.77 | 1.21 ± 11.70 | −0.062 | −1.51 | −4.99; 1.96 | 0.39 |
Role limitations physical | −5.32 ± 32.77 | 4.84 ± 32.61 | −0.138 | −8.9 | −17.16; −0.65 | 0.04† |
Bodily pain | −0.24 ± 19.33 | 2.40 ± 16.59 | −0.07 | −2.52 | −7.30; 2.27 | 0.3 |
General health perceptions | 0.37 ± 13.39 | 3.10 ± 13.61 | −0.063 | −1.71 | −5.44; 2.02 | 0.37 |
Mental health | −1.68 ± 11.78 | −0.12 ± 13.09 | −0.033 | −0.83 | −4.42; 2.77 | 0.65 |
Role limitations emotional | −3.72 ± 34.92 | 1.08 ± 33.50 | −0.063 | −4.31 | −13.00; 4.37 | 0.31 |
Vitality | −2.71 ± 13.35 | −1.00 ± 12.17 | −0.064 | −1.62 | −5.11; 1.88 | 0.36 |
Social functioning‡ | 0.00 (−12.50 to 0.00) | 0.00 (−12.50 to 0.00) | 0.95 | 0.95 | 0.80; 1.11 | 0.49 |
Physical component summary | −1.50 ± 13.82 | 2.89 ± 11.39 | −0.15 | −3.77 | −7.26; −0.28 | 0.04† |
Mental component summary‡ | 0.79 (−6.38 to 6.00) | 0.00 (−4.50 to 7.50) | 0.93 | 0.97 | 0.91; 1.04 | 0.34 |
A positive β value indicates an increase in the SF-36 domain in the vitamin D group compared to the placebo group.
Adjusted for age, gender, BMI, baseline SF-36 domain, baseline 25-hydroxyvitamin and season of blood collection; †P < 0.05; ‡Using log-transformed values; β of 0.95 (social functioning) indicating a 5% lower SF-36 score in the vitamin D group vs the placebo group after six months.